Non-coordinate regulation of enzymes involved in transfer RNA metabolism in Escherichia coli.
1980 (English)In: Biochimica et Biophysica Acta, ISSN 0006-3002, Vol. 607, no 2, 277-84 p.Article in journal (Refereed) Published
During different steady state growth conditions in Escherichia coli the level of the three tRNA-modifying enzymes, the tRNA(m5Urd)-, tRNA(m1Guo)- and tRNA(mam5s2Urd)methyltransferase and of five aminoacyl-tRNA synthetases, the leucyl-, valyl-, isoleucyl-, arginyl- and threonyl-tRNA-synthetase, has been determined. It is shown that those two classes of tRNA affecting enzymes are not coordinately regulated and that even within these two groups of enzymes the constituents are regulated independently of each other. Furthermore it is demonstrated that none of the aminoacyl-tRNA synthetases and only one of the three tRNA-methyltransferases, the tRNA(m5Urd)methyltransferase, is under control of the relA+-gene.
Place, publisher, year, edition, pages
1980. Vol. 607, no 2, 277-84 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:umu:diva-59750PubMedID: 6154481OAI: oai:DiVA.org:umu-59750DiVA: diva2:556420