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Tissue-type plasminogen activator gene is on chromosome 8.
Umeå University, Faculty of Medicine, Department of Medical Biochemistry and Biophysics.
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1986 (English)In: Cytogenetics and Cell Genetics, ISSN 0301-0171, E-ISSN 1421-9816, Vol. 42, no 1-2, 24-8 p.Article in journal (Refereed) Published
Abstract [en]

Tissue plasminogen activator is one of the two plasminogen activators, both serine proteases, that catalyze the conversion of inactive plasminogen to plasmin, which then degrades the fibrin network of blood clots. By combining somatic cell genetics, in situ hybridization, and Southern blot hybridization, we localized the human tissue plasminogen activator gene to the pericentromeric region of chromosome 8.

Place, publisher, year, edition, pages
1986. Vol. 42, no 1-2, 24-8 p.
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Medical and Health Sciences
URN: urn:nbn:se:umu:diva-59876PubMedID: 3087707OAI: diva2:556974
Available from: 2012-09-26 Created: 2012-09-26 Last updated: 2012-09-26

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