Neuromotor and cognitive functions in 4-9-years-old children born prematurely
2011 (English)In: Developmental Medicine & Child Neurology, ISSN 0012-1622, E-ISSN 1469-8749, Vol. 53, no Suppl. s3, 33-34 p.Article in journal, Meeting abstract (Refereed) Published
OBJECTIVE: To identifying developmental differences in neurologically based functioning in preterm born children compared with typically developing, fullterm born children. BACKGROUND: Resent follow-up studies of children born prematurely, even in those without identified neuropathology, have consistently found poorer neuromotor and cognitive skills at school age; thus, at least from group level comparisons. Still, our knowledge is limited in how a preterm birth may effects later behavioural outcomes. DESIGN/METHODS: In the first phase of this ongoing, cross-sectional and quasi-longitudinal study, motor functions, laterality and cognitive functions have been investigated in 4-9-years-old children born prematurely (N= 70, Mean GW=31), and in comparison to age matched fullterm born children (N=78). Additionally, brain imaging (MRI) data was collected on both fullterm and preterm born children at the age of 7-9-years. Kinematic movement registrations and additional behaviour measurements in combination with high resolution, structural 3Tesla MRI scans was used to investigate a number of expected crucial issues and associations between neuromotor, cognitive and structural organisations in both the preterm and the full term born children. RESULTS: Preliminary outcomes indicating subtitle, but still overall differences in most of the kinematic parameters analysed from arm, hand, and head movements (e.g., movement durations, smoothes, segmentation, velocity profile), and with less lateralized sensory-motor performance in the preterm born children at the age of 4- and 7-9-years in comparison to fullterm born children. In addition, the kinematic outcomes were associated with the cognitive performance in the preterm born children. These results are suggesting that both neuromotor and cognitive functions are less efficient in preterm born children. These behavioural outcomes will further be investigated in relation to the outcomes from the MRI investigations. CONCLUSIONS: The outcome from the first analysis underscores the need for further refine investigations and follow-ups, even on an individual level, for the majority of preterm born children.
Place, publisher, year, edition, pages
2011. Vol. 53, no Suppl. s3, 33-34 p.
IdentifiersURN: urn:nbn:se:umu:diva-60042OAI: oai:DiVA.org:umu-60042DiVA: diva2:557796