The Mediterranean Diet Score and Mortality Are Inversely Associated in Adults Living in the Subarctic Region
2012 (English)In: Journal of Nutrition, ISSN 0022-3166, E-ISSN 1541-6100, Vol. 142, no 8, 1547-1553 p.Article in journal (Refereed) Published
The Mediterranean diet has been widely promoted and may be associated with chronic disease prevention and a better overall health status. The aim of this study was to evaluate whether the Mediterranean diet score inversely predicted total or cause-specific mortality in a prospective population study in Northern Sweden (Vasterbotten Intervention Program). The analyses were performed in 77,151 participants (whose diet was measured by means of a validated FFQ) by Cox proportional hazard models adjusted for several potential confounders. The Mediterranean diet score was inversely associated with all-cause mortality in men [HR = 0.96(95% Cl = 0.93, 0.99)] and women [HR = 0.95 (95% Cl = 0.91, 0.99)], although not in obese men. In men, but not in women, the score was inversely associated with total cancer mortality [HR = 0.92 (95% Cl = 0.87, 0.98)], particularly for pancreas cancer [HR = 0.82 (95% Cl = 0.68, 0.99)]. Cardiovascular mortality was inversely associated with diet only in women [HR = 0.90(95% Cl = 0.82, 0.99)]. Except for alcohol [HR = 0.83(95% Cl = 0.76, 0.90)] and fruit intake [HR = 0.90 (95% Cl = 0.83, 0.98)], no food item of the Mediterranean diet score independently predicted mortality. Higher scores were associated with increasing age, education, and physical activity. Moreover, healthful dietary and lifestyle-related factors additively decreased the mortality likelihood. Even in a subarctic region, increasing Mediterranean diet scores were associated with a longer life, although the protective effect of diet was of small magnitude compared with other healthful dietary and lifestyle-related factors examined.
Place, publisher, year, edition, pages
American Society for Nutrition , 2012. Vol. 142, no 8, 1547-1553 p.
Nutrition and Dietetics
IdentifiersURN: urn:nbn:se:umu:diva-59730DOI: 10.3945/jn.112.160499ISI: 000306865200019OAI: oai:DiVA.org:umu-59730DiVA: diva2:561500
FunderForte, Swedish Research Council for Health, Working Life and WelfareSwedish Research Council