umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Pollen exposure in pregnancy and infancy and risk of asthma hospitalisation: a register based cohort study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health. Murdoch Children’s Research Institute; Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. Department of Research and Development, Västernorrland County Council.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
2012 (English)In: Allergy, Asthma & Clinical Immunology, ISSN 1710-1484, E-ISSN 1710-1492, Vol. 8, no 1, 17Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: A seasonal effect of month of birth and risk of allergic disease has been suggested by numerous studies. Few studies have directly measured pollen exposures at different points during pregnancy and in early life, and assessed their effects on risk of respiratory disease outcomes.

METHODS: Pollen exposure was calculated for the first and last 12 weeks of pregnancy and the first 12 weeks of infancy for all children conceived by women residing in Stockholm, Sweden, between 1988 and 1995. Hospital admission data for respiratory conditions in the first year of life was also collected.

RESULTS: Out of 110,381 children, 940 had been hospitalised for asthma by 12-months of age. Pollen levels showed both marked seasonal variations and between year differences. Exposure to high levels of pollen in the last 12 weeks of pregnancy was associated with an increased risk of asthma hospitalisation (aOR = 1.35, 95% CI = 1.07-1.71 for highest quartile versus remaining infants). Exposure to high levels of pollen in the first three months of life was associated with a reduced risk (aOR = 0.76, 95% CI = 0.59-0.98) but only in children of heavy smoking mothers.

CONCLUSIONS: High levels of pollen exposure during late pregnancy were somewhat unexpectedly associated with an elevated risk of hospitalisation for asthma within the first year of life.

Place, publisher, year, edition, pages
BioMed Central, 2012. Vol. 8, no 1, 17
Keyword [en]
Pollen, Early life exposure, Asthma, Hospitalisation
National Category
Environmental Health and Occupational Health Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:umu:diva-61468DOI: 10.1186/1710-1492-8-17ISI: 000208875200017PubMedID: 23134739OAI: oai:DiVA.org:umu-61468DiVA: diva2:567988
Available from: 2012-11-15 Created: 2012-11-15 Last updated: 2017-12-07Bibliographically approved

Open Access in DiVA

fulltext(405 kB)100 downloads
File information
File name FULLTEXT02.pdfFile size 405 kBChecksum SHA-512
22525d51e745c5674941e9d3338bf3e4663e8b7ada3524f10e9e24c29fed7836cb65571212ff81ab2abf1dcd2ecb4431e8fd68ef8147bb6f3074975246b1aba5
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Lowe, Adrian JOlsson, DavidBråbäck, LennartForsberg, Bertil

Search in DiVA

By author/editor
Lowe, Adrian JOlsson, DavidBråbäck, LennartForsberg, Bertil
By organisation
Occupational and Environmental MedicineEpidemiology and Global Health
In the same journal
Allergy, Asthma & Clinical Immunology
Environmental Health and Occupational HealthRespiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar
Total: 100 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 141 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf