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An efficient procedure for the synthesis of formylacetic esters
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Science and Technology, Department of Chemistry.
2012 (English)In: Tetrahedron Letters, ISSN 0040-4039, E-ISSN 1359-8562, Vol. 53, no 50, 6819-6821 p.Article in journal (Refereed) Published
Abstract [en]

An efficient synthesis of formylacetic esters via ozonolysis of trans-beta-hydromuconic esters followed by a solid-supported triphenylphosphine reduction has been developed. In addition, an extension toward formylacetic amides and a one-pot preparation of more stable intermediates which can be used for further transformations are also described.

Place, publisher, year, edition, pages
2012. Vol. 53, no 50, 6819-6821 p.
Keyword [en]
Formylacetic esters, Ozonolysis, Solid phase scavenging, Heterocycles
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:umu:diva-63010DOI: 10.1016/j.tetlet.2012.10.021ISI: 000311473500022OAI: oai:DiVA.org:umu-63010DiVA: diva2:581672
Available from: 2013-01-02 Created: 2012-12-27 Last updated: 2017-12-06Bibliographically approved

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Edvinsson, SofieJohansson, SusanneLarsson, Andreas

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