Computational estimation of fluid mechanical benefits from a fluid deflector at the distal end of artificial vascular grafts
2013 (English)In: Computers in Biology and Medicine, ISSN 0010-4825, E-ISSN 1879-0534, Vol. 43, no 2, 164-168 p.Article in journal (Refereed) Published
Intimal hyperplasia at the distal anastomosis is considered to be an important determinant for arterial and arteriovenous graft failure. The connection between unhealthy hemodynamics and intimal hyperplasia motivates the use of computational fluid dynamics modeling to search for improved graft design. However, studies on the fluid mechanical impact on intimal hyperplasia at the suture line intrusion have previously been scanty. In the present work, we focus on intimal hyperplasia at the suture line and illustrate potential benefits from the introduction of a fluid deflector to shield the suture line from unhealthily high wall shear stress.
Place, publisher, year, edition, pages
Pergamon-Elsevier Science , 2013. Vol. 43, no 2, 164-168 p.
Vascular bypass, Artificial grafts, CFD modeling, Wall shear stress, Computational design evaluation
Computer and Information Science Biological Sciences
IdentifiersURN: urn:nbn:se:umu:diva-67042DOI: 10.1016/j.compbiomed.2012.11.012ISI: 000314560800011OAI: oai:DiVA.org:umu-67042DiVA: diva2:611362