Deep brain stimulation: effects on swallowing function in Parkinson's disease
2013 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 127, no 5, 329-336 p.Article in journal (Refereed) Published
Objective: In patients with Parkinson’s disease (PD), deep brainstimulation of the subthalamic nucleus (STN DBS) is well recognizedin improving limb function, but the outcome on swallowing functionhas rarely been studied. The aim of this work was to evaluate theeffect of STN DBS on pharyngeal swallowing function in patientswith PD using self-estimation and ﬁberoptic endoscopic evaluation ofswallowing.
Methods: Eleven patients (aged 41–72, median 61 years)were evaluated preoperatively and at 6 and 12 months after STN DBSsurgery. All patients were evaluated with self-estimation on a visualanalogue scale, and eight of them with a ﬁberoptic endoscopicexamination with a predeﬁned swallowing protocol includingRosenbek’s Penetration-Aspiration Scale, Secretion Severity Scale,preswallow spillage, pharyngeal residue, and pharyngeal clearance.
Results: The self-assessments of swallowing function revealed asubjective improvement with STN DBS stimulation, whereas the datafrom the swallowing protocol did not show any signiﬁcant effect ofthe STN DBS treatment itself. The prevalence of aspiration was notaffected by the surgery.
Conclusions: The results show thatswallowing function was not negatively affected by STN DBS and therisk of aspiration did not increase. Self-estimation of swallowingfunction showed a subjective improvement due to stimulation
Place, publisher, year, edition, pages
Wiley and sons: John Wiley & Sons, 2013. Vol. 127, no 5, 329-336 p.
deep brain stimulation; subthalamic nucleus; dysphagia; Parkinson’s disease; fiberoptic endoscopic evaluation of swallowing; swallowing function; aspiration; L-dopa
Research subject Medicine
IdentifiersURN: urn:nbn:se:umu:diva-61453DOI: 10.1111/ane.12019OAI: oai:DiVA.org:umu-61453DiVA: diva2:615326
ProjectsSpeech, voice and swallowing outcomes after deep brain stimulation (DBS)