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Adverse changes in fibre type and myosin heavy chain compositions of human jaw muscle vs. limb muscle during ageing.
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB), Anatomy.
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1999 (English)In: Acta Physiologica Scandinavica, ISSN 0001-6772, E-ISSN 1365-201X, Vol. 167, no 4, 339-45 p.Article in journal (Refereed) Published
Abstract [en]

This review shows that human jaw muscles not only have unique fibre type and myosin heavy chain (MyHC) compositions but also undergo muscle and region-specific changes in fibre composition during ageing. Alterations in the masseter and the lateral pterygoid muscles in the elderly are opposite to those reported for limb and trunk muscles, whereas changes in the anterior and posterior bellies of the digastric muscle resemble those of limb and trunk muscles. We conclude that age-related alterations in fibre type composition and MyHC expression are muscle and region specific, probably reflecting muscular differences in genetic programs and epigenetic influences.

Place, publisher, year, edition, pages
1999. Vol. 167, no 4, 339-45 p.
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Cell and Molecular Biology
URN: urn:nbn:se:umu:diva-68861PubMedID: 10632637OAI: diva2:618382
Available from: 2013-04-26 Created: 2013-04-26 Last updated: 2013-04-26

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