Change search
ReferencesLink to record
Permanent link

Direct link
Higher heart rate increases risk of diabetes among men: the Australian Diabetes Obesity and Lifestyle (AusDiab) Study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology.
Show others and affiliations
2013 (English)In: Diabetic Medicine, ISSN 0742-3071, E-ISSN 1464-5491, Vol. 30, no 4, 421-427 p.Article in journal (Refereed) Published
Abstract [en]

Aims A very limited number of prospective studies have reported conflicting data on the relation between heart rate and diabetes risk. Our aim therefore was to determine in a large, national, population-based cohort if heart rate predicts the development of diabetes. Methods The Australian Diabetes Obesity and Lifestyle study followed up 6537 people over 5years. Baseline measurements included questionnaires, anthropometrics and blood and urine collection. Heart rate was recorded in beats per min (Dinamap). An oral glucose tolerance test was performed at baseline and follow-up, and diabetes was defined using World Health Organization criteria. Results A total of 5817 participants were eligible for analysis, 221 of whom developed diabetes. Compared with participants with a heart rate <60bmin1, those with a heart rate 80bmin1 were more likely to develop diabetes (odds ratio1.89, 95%CI 1.073.35) over 5years, independent of traditional risk factors. This relationship was highly significant, particularly in non-obese men (odds ratio5.61, 95%CI 1.7517.98), but not in their obese counterparts or in women. Conclusions Resting heart rate is associated with an increased risk of diabetes over a 5-year period, particularly among non-obese men. This suggests that sympathetic overactivity may be a contributing factor to the development of diabetes, and that resting heart rate may be useful in predicting risk of Type2 diabetes in non-obese men.

Place, publisher, year, edition, pages
2013. Vol. 30, no 4, 421-427 p.
National Category
Endocrinology and Diabetes
URN: urn:nbn:se:umu:diva-68895DOI: 10.1111/dme.12045ISI: 000316465400011OAI: diva2:621774
Available from: 2013-05-17 Created: 2013-04-29 Last updated: 2013-05-17Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Söderberg, Stefan
By organisation
In the same journal
Diabetic Medicine
Endocrinology and Diabetes

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 36 hits
ReferencesLink to record
Permanent link

Direct link