Change search
ReferencesLink to record
Permanent link

Direct link
Effects of delayed cord clamping on neurodevelopment and infection at four months of age: a randomised trial
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Paediatrics.
2013 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 102, no 5, 525-531 p.Article in journal (Refereed) Published
Abstract [en]

Aim To investigate the effect that delayed and early umbilical cord clamping have on neurodevelopment, immunoglobulin G (IgG) and symptoms of infection during the first 4months of life.

Methods Full-term infants (n=382) were randomised to delayed (180sec) or early cord clamping (10sec). The Ages and Stages Questionnaire (ASQ) was used to assess neurodevelopment at 4months. Immunoglobulin G was measured at birth, 23days and 4months. Parents recorded any symptoms indicating infection during the first 4months of life.

Results The total scores from the ASQ did not differ between groups. However, the delayed cord clamping (DCC) group had a higher mean (SD) score in the problem-solving domain [55.3 (7.2) vs. 53.5 (8.2), p=0.03] at 4months and a lower mean (SD) score in the personal-social domain [49.5 (9.3) vs. 51.8 (8.1), p=0.01]. The IgG level was higher in the DCC group at 23days (11.7 vs. 11.0g/L, p=0.004), but did not differ between the groups at 4months. Symptoms of infection were comparable between the groups.

Conclusion Delayed cord clamping did not affect overall neurodevelopment or symptoms of infection up to 4months of age, but may have an impact on specific neurodevelopmental domains.

Place, publisher, year, edition, pages
2013. Vol. 102, no 5, 525-531 p.
Keyword [en]
Infant, Infection, Neurodevelopment, Umbilical cord clamping
National Category
URN: urn:nbn:se:umu:diva-71075DOI: 10.1111/apa.12168ISI: 000317361400029OAI: diva2:629656
Available from: 2013-06-17 Created: 2013-05-20 Last updated: 2013-06-17Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Domellöf, Magnus
By organisation
In the same journal
Acta Paediatrica

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 71 hits
ReferencesLink to record
Permanent link

Direct link