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Structure-function correlates of episodic memory in aging
Department of Psychology, Stockholm University, Stockholm.
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB). Umeå University, Faculty of Medicine, Department of Radiation Sciences.
2008 (English)In: Handbook of Episodic Memory, Elsevier, 2008, 521-535 p.Chapter in book (Refereed)
Abstract [en]

Normal aging is accompanied by a wide variety of disturbances in the structure and function of the human brain. It is now well established that normal aging is associated with a progressive decline of episodic-memory function, especially in cued and free recall tasks. Although the primary causes of this decline remain elusive, neuroimaging research have presented an avenue for understanding age-related episodic-memory failure. By integrating behavioral measures and imaging data, the relationship between biological markers of aging and cognitive functions can be explored. In this chapter, we review current knowledge about the effects of normal aging, and its neural correlates as revealed by functional and structural neuroimaging. The importance of reliable cognitive measures in aging research, such as longitudinal behavioral assessment, is also highlighted. We also present results that attempt at characterizing cognitive aging at multiple levels by integrating structural, neuroimaging, and episodic-memory measures.

Place, publisher, year, edition, pages
Elsevier, 2008. 521-535 p.
, Handbook of Behavioral Neuroscience, ISSN 1569-7339 ; 18
Keyword [en]
episodic, prefrontal, aging, fMRI, longitudinal, memory, compensation, hippocampus, diffusion-tensor imaging, corpus callosum
National Category
URN: urn:nbn:se:umu:diva-76177DOI: 10.1016/S1569-7339(08)00228-2ISI: 000311452400029ISBN: 978-0-08-093236-1OAI: diva2:635594

Pages 521–535 and 633–634.

Available from: 2013-07-04 Created: 2013-07-04 Last updated: 2013-07-04Bibliographically approved

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Nyberg, Lars
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Department of Integrative Medical Biology (IMB)Department of Radiation Sciences

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ReferencesLink to record
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