An in vitro evaluation of the biological effects of carbon nanotube-coated dental zirconia
2013 (English)In: ISRN Dentistry, ISSN 2090-4371, E-ISSN 2090-438X, Vol. 2013, no Article ID 296727Article in journal (Refereed) Published
The purpose of this study is to evaluate functionalized multiwalled carbon nanotubes (fMWCNTs) as a potential coating material for dental zirconia from a biological perspective: its effect on cell proliferation, viability, morphology, and the attachment of an osteoblast-like cell. Osteoblast-like (Saos-2) cells were seeded on uncoated and fMWCNT-coated zirconia discs and in culture dishes that served as controls. The seeding density was 104 cells/cm2, and the cells were cultured for 6 days. Cell viability, proliferation and attachment of the Saos-2 cells were studied. The results showed that Saos-2 cells were well attached to both the uncoated and the fMWCNT-coated zirconia discs. Cell viability and proliferation on the fMWCNT-coated zirconia discs were almost the same as for the control discs. Better cell attachment was seen on the fMWCNT-coated than on the uncoated zirconia discs. In conclusion, fMWCNTs seem to be a promising coating material for zirconia-based ceramic surfaces to increase the roughness and thereby enhance the osseointegration of zirconia implants.
Place, publisher, year, edition, pages
United States: Hindawi Publishing Corporation, 2013. Vol. 2013, no Article ID 296727
IdentifiersURN: urn:nbn:se:umu:diva-78252DOI: 10.1155/2013/296727OAI: oai:DiVA.org:umu-78252DiVA: diva2:637340