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An in vitro evaluation of the biological effects of carbon nanotube-coated dental zirconia
Umeå University, Faculty of Medicine, Department of Odontology.
Department of Biomedical Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan..
Department of Biomedical Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan..
Umeå University, Faculty of Medicine, Department of Odontology.
2013 (English)In: ISRN Dentistry, ISSN 2090-4371, E-ISSN 2090-438X, Vol. 2013, no Article ID 296727Article in journal (Refereed) Published
Abstract [en]

The purpose of this study is to evaluate functionalized multiwalled carbon nanotubes (fMWCNTs) as a potential coating material for dental zirconia from a biological perspective: its effect on cell proliferation, viability, morphology, and the attachment of an osteoblast-like cell. Osteoblast-like (Saos-2) cells were seeded on uncoated and fMWCNT-coated zirconia discs and in culture dishes that served as controls. The seeding density was 104 cells/cm2, and the cells were cultured for 6 days. Cell viability, proliferation and attachment of the Saos-2 cells were studied. The results showed that Saos-2 cells were well attached to both the uncoated and the fMWCNT-coated zirconia discs. Cell viability and proliferation on the fMWCNT-coated zirconia discs were almost the same as for the control discs. Better cell attachment was seen on the fMWCNT-coated than on the uncoated zirconia discs. In conclusion, fMWCNTs seem to be a promising coating material for zirconia-based ceramic surfaces to increase the roughness and thereby enhance the osseointegration of zirconia implants.

Place, publisher, year, edition, pages
United States: Hindawi Publishing Corporation, 2013. Vol. 2013, no Article ID 296727
Keyword [en]
carbon-nanotube, MWCNTs
National Category
Dentistry
Identifiers
URN: urn:nbn:se:umu:diva-78252DOI: 10.1155/2013/296727OAI: oai:DiVA.org:umu-78252DiVA: diva2:637340
Available from: 2013-07-17 Created: 2013-07-17 Last updated: 2017-12-06Bibliographically approved

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Kou, WenSjögren, Göran

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