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Synthesis and NMR elucidation of homoisoflavanone analogues
School of Chemistry, University of KwaZulu-Natal, Durban, South Africa .
2011 (English)In: Structural Chemistry, ISSN 1040-0400, E-ISSN 1572-9001, Vol. 22, no 1, 161-166 p.Article in journal (Refereed) Published
Abstract [en]

A series of five homoisoflavanone analogues have been synthesized from the corresponding 3,5-methoxy phenols via chroman-4-one in three steps. The complete NMR elucidation of these homoisoflavanone analogues is reported. The use of 2D NMR techniques (COSY, NOESY, HSQC and HMBC) proved to be very useful tools in the elucidation of homoisoflavanone analogues. The homoisoflavanone analogues exhibit an AA'BB' spin pattern in the ring B of the homoisoflavanone. These homoisoflavanone analogues are potential antifungal and anti-inflammatory agents.

Place, publisher, year, edition, pages
2011. Vol. 22, no 1, 161-166 p.
National Category
Medicinal Chemistry
URN: urn:nbn:se:umu:diva-80018DOI: 10.1007/s11224-010-9703-xISI: 000286983500019OAI: diva2:646156
Available from: 2013-09-06 Created: 2013-09-06 Last updated: 2013-09-24Bibliographically approved

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Petzold, Katja
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