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Effects of FESS and additional fluticasone propionate nasal drops on psychological well-being in nasal polyposis with asthma
Umeå University, Faculty of Social Sciences, Department of Psychology.
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden. (Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden)
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2013 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 133, no 9, 939-943 p.Article in journal (Refereed) Published
Abstract [en]

Conclusion: A combined therapy of fluticasone propionate nasal drops (FPND) and functional endoscopic sinus surgery (FESS) can improve quality of life (QoL). When compared with prior data, the results imply that a generic measure of psychological aspects of QoL may be better than measures of respiratory symptoms and clinical parameters to capture a patient's perception of the disease and its treatment. Objective: To better understand effects of FPND and FESS on generic QoL. Methods: Sixty nasal polyposis patients with concomitant asthma completed participation in a randomized, double-blind, placebo-controlled, 14-week study in which they responded to the General Well-Being Schedule (GWBS). Results: GWBS scores (i) increased significantly after administration of FPND, independent of FESS (from lower than normal to normal), (ii) increased after FESS independent of FPND (from lower than normal to normal), and (iii) increased additively after FPND and FESS.

Place, publisher, year, edition, pages
Informa Healthcare, 2013. Vol. 133, no 9, 939-943 p.
Keyword [en]
Functional endoscopic sinus surgery, General Well-Being Schedule, quality of life, randomized controlled trial
National Category
Otorhinolaryngology
Identifiers
URN: urn:nbn:se:umu:diva-81477DOI: 10.3109/00016489.2013.783715ISI: 000323244700008OAI: oai:DiVA.org:umu-81477DiVA: diva2:655703
Available from: 2013-10-13 Created: 2013-10-13 Last updated: 2017-12-06Bibliographically approved

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