Change search
ReferencesLink to record
Permanent link

Direct link
Olfactory loss after head and neck cancer radiation therapy
Department of Otorhinolaryngology, Central Hospital, Skövde, Sweden.
Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Umeå University, Faculty of Social Sciences, Department of Psychology.
Department of Otorhinolaryngology, Central Hospital, Skövde, Sweden.
2013 (English)In: Rhinology, ISSN 0300-0729, Vol. 51, no 3, 206-209 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: A reduced sense of smell may be one explanation for why patients with cancer in the ear, nose and throat (ENT) region who are treated with radiation therapy lose weight. The purpose of this study was to investigate whether radiation therapy has a negative effect on olfactory function and, if so, whether this effect is dose-related.

METHODOLOGY: Seventy-one patients were tested using odour-detection sensitivity and olfactory identification tests before radiation therapy and 20 months after it.

RESULTS: Patients who received radiation close to the olfactory organ showed a reduced sense of smell, in both tests. A multiple regression analysis showed that the radiation dose was related to decline in the olfactory function, while age, sex, chemotherapy and interactions between these variables were not.

CONCLUSION: Radiation therapy can damage olfactory cells.

Place, publisher, year, edition, pages
2013. Vol. 51, no 3, 206-209 p.
Keyword [en]
smell/radiation effects, radiotherapy/adverse effects, head and neck neoplasms, humans, adults
National Category
Psychology Otorhinolaryngology
URN: urn:nbn:se:umu:diva-81478DOI: 10.4193/Rhino12.120ISI: 000332267900003PubMedID: 23943726OAI: diva2:655707
Available from: 2013-10-13 Created: 2013-10-13 Last updated: 2014-04-07Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Nordin, Steven
By organisation
Department of Psychology
In the same journal

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 34 hits
ReferencesLink to record
Permanent link

Direct link