Change search
ReferencesLink to record
Permanent link

Direct link
Combined low-saturated fat intake and high fitness may counterbalance diabetogenic effects of obesity: the DR's EXTRA Study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Show others and affiliations
2013 (English)In: European Journal of Clinical Nutrition, ISSN 0954-3007, E-ISSN 1476-5640, Vol. 67, no 9, 1000-1002 p.Article in journal (Refereed) Published
Abstract [en]

We report associations of saturated fat (SF) intake with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), concurrent IFG+IGT and type 2 diabetes (T2DM) at different levels of cardiorespiratory fitness and body mass index (BMI). In a population-based sample (n = 1261, age 58-78 years), oral glucose tolerance, 4-day food intake and maximal oxygen uptake were measured. High intake of SF (>11.4 E%) was associated with elevated risk for IFG (4.36; 1.93-9.88), concurrent IFG+IGT (6.03; 1.25-29.20) and T2DM (4.77; 1.93-11.82) in the category of high BMI (>26.5) and high fitness, whereas there was no significantly elevated risk in individuals reporting low intake of SF. Concurrent high BMI and low fitness were associated with elevated risks. In general, SF intake and fitness did not differentiate the risk of abnormal glucose metabolism among subjects with low BMI. Limited intake of SF may protect from diabetogenic effects of adiposity, but only in individuals with high level of fitness.

Place, publisher, year, edition, pages
Nature Publishing Group, 2013. Vol. 67, no 9, 1000-1002 p.
Keyword [en]
cardiovascular fitness, diet, food habits, lifestyle, obesity, saturated fat
National Category
Nutrition and Dietetics
URN: urn:nbn:se:umu:diva-81308DOI: 10.1038/ejcn.2013.138ISI: 000324170800020OAI: diva2:656155
Available from: 2013-10-15 Created: 2013-10-07 Last updated: 2013-10-15Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Krachler, Benno
By organisation
Occupational and Environmental Medicine
In the same journal
European Journal of Clinical Nutrition
Nutrition and Dietetics

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 34 hits
ReferencesLink to record
Permanent link

Direct link