umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Universal soldier: Pseudomonas aeruginosa - an opportunistic generalist
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
Visa övriga samt affilieringar
2013 (Engelska)Ingår i: Frontiers in Biology, ISSN 1674-7984, Vol. 8, nr 4, s. 387-394Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The opportunistic pathogen Pseudomonas aeruginosa commonly causes chronic and ultimately deadly lung infections in individuals with the genetic disease cystic fibrosis (CF). P. aeruginosa is metabolically diverse; it displays a remarkable ability to adapt to and successfully occupy almost any niche, including the ecologically complex CF lung. These P. aeruginosa lung infections are a fascinating example of microbial evolution within a "natural" ecosystem. Initially, P. aeruginosa shares the lung niche with a plethora of other microorganisms and is vulnerable to antibiotic challenges. Over time, adaptive evolution leads to certain commonly-observed phenotypic changes within the P. aeruginosa population, some of which render it resistant to antibiotics and apparently help it to out-compete the other species that co-habit the airways. Improving genomics techniques continue to elucidate the evolutionary mechanisms of P. aeruginosa within the CF lung and will hopefully identify new vulnerabilities in this robust and versatile pathogen. © 2013 Higher Education Press and Springer-Verlag Berlin Heidelberg.

Ort, förlag, år, upplaga, sidor
Springer, 2013. Vol. 8, nr 4, s. 387-394
Nyckelord [en]
adaptive radiation, antibiotic resistance, cystic fibrosis, evolution, Pseudomonas aeruginosa, quorum sensing
Nationell ämneskategori
Kemi
Identifikatorer
URN: urn:nbn:se:umu:diva-82585DOI: 10.1007/s11515-013-1267-xOAI: oai:DiVA.org:umu-82585DiVA, id: diva2:661994
Tillgänglig från: 2013-11-05 Skapad: 2013-11-05 Senast uppdaterad: 2018-06-08Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltext

Personposter BETA

Rzhepishevska, OlenaRamstedt, Madeleine

Sök vidare i DiVA

Av författaren/redaktören
Rzhepishevska, OlenaRamstedt, Madeleine
Av organisationen
Kemiska institutionen
Kemi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 324 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf