Failure to detect Chlamydia trachomatis in cell culture by using a monoclonal antibody directed against the major outer membrane protein
1997 (English)In: Journal of Clinical Microbiology, ISSN 0095-1137, E-ISSN 1098-660X, Vol. 35, no 10, 2679-2680 p.Article in journal (Refereed) Published
Two commercially available monoclonal antibodies for cell culture confirmation of Chlamydia trachomatis were compared in two prospective studies and one large retrospective study. In total, more than 33,000 genital specimens were cultured in parallel and stained with both antibodies, one of which was directed against the major outer membrane protein (MOMP) and one uf which was directed against the lipopolysaccharide (LPS). We found the anti-LPS-based assay to be more sensitive and as specific as the anti-MOMP-based assay for C. trachomatis cell culture confirmation of genital specimens.
Place, publisher, year, edition, pages
1997. Vol. 35, no 10, 2679-2680 p.
Clinical Laboratory Medicine Dermatology and Venereal Diseases
IdentifiersURN: urn:nbn:se:umu:diva-83409ISI: A1997XX18200050PubMedID: 9316934OAI: oai:DiVA.org:umu-83409DiVA: diva2:666764