Whole Grain Intake and Survival Among Scandinavian Colorectal Cancer Patients
2014 (English)In: Nutrition and Cancer, ISSN 0163-5581, E-ISSN 1532-7914, Vol. 66, no 1, 6-13 p.Article in journal (Refereed) Published
To our knowledge, no studies of associations between intake of whole grain (WHG) and survival of colorectal cancer have been published, despite evidence that dietary fiber, and to some extent WHG, are associated with lower risk of colorectal cancer. Scandinavia is an area where the WHG consumption traditionally is high. We performed a case-only (N = 1119) study in the Scandinavian HELGA cohort of pre-diagnosis WHG intake (total WHG, WHG wheat, WHG rye, and WHG oats) and survival of colorectal cancer. Cox regression analyses were used to study the associations, both in categorical and continuous models, stratified by location (proximal, distal, rectum) and country. No evidence of an association was found, neither for total WHG intake (hazard ratio = 1.32, 95% confidence interval: 0.88-1.97 lowest vs. highest tertile, adjusted for age at diagnosis, metastasis status, smoking, folate, margarine, and energy), nor for specific grains. Prediagnosis consumption of WHG does not seem to improve survival of colorectal cancer in subjects diagnosed within this prospective population-based Scandinavian cohort.
Place, publisher, year, edition, pages
Routledge, 2014. Vol. 66, no 1, 6-13 p.
nutrition, whole grain, survival, colorectal cancer
Nutrition and Dietetics Public Health, Global Health, Social Medicine and Epidemiology
IdentifiersURN: urn:nbn:se:umu:diva-84004DOI: 10.1080/01635581.2014.847472ISI: 000329141100002PubMedID: 24274588OAI: oai:DiVA.org:umu-84004DiVA: diva2:678550
FunderSwedish Research CouncilForte, Swedish Research Council for Health, Working Life and WelfareSwedish Cancer Society