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Signaling pathways regulating ectodermal cell fate choices
Umeå University, Faculty of Medicine, Umeå Centre for Molecular Medicine (UCMM).
Umeå University, Faculty of Medicine, Umeå Centre for Molecular Medicine (UCMM).
2014 (English)In: Experimental Cell Research, ISSN 0014-4827, E-ISSN 1090-2422, Vol. 321, no 1, 11-16 p.Article, review/survey (Refereed) Published
Abstract [en]

Although embryonic patterning and early development of the nervous system have been studied for decades, our understanding of how signals instruct ectodermal derivatives to acquire specific identities has only recently started to form a coherent picture. In this mini-review, we summarize recent findings and models of how a handful of well-known secreted signals influence progenitor cells in successive binary decisions to adopt various cell type specific differentiation programs.

Place, publisher, year, edition, pages
2014. Vol. 321, no 1, 11-16 p.
Keyword [en]
Ectoderm, Neural crest, Placodes, Cell specification, BMP, Wnt, FGF, Shh
National Category
Cancer and Oncology Cell Biology
Identifiers
URN: urn:nbn:se:umu:diva-87036DOI: 10.1016/j.yexcr.2013.08.002ISI: 000331157200003OAI: oai:DiVA.org:umu-87036DiVA: diva2:710535
Available from: 2014-04-07 Created: 2014-03-18 Last updated: 2017-12-05Bibliographically approved

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Patthey, CedricGunhaga, Lena

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