Change search
ReferencesLink to record
Permanent link

Direct link
Group B streptococcus in prosthetic hip and knee joint-associated infections
Show others and affiliations
2011 (English)In: Journal of Hospital Infection, ISSN 0195-6701, E-ISSN 1532-2939, Vol. 79, no 1, 64-69 p.Article in journal (Refereed) Published
Abstract [en]

The incidence of invasive group B streptococcus (GBS) infections in non-pregnant adults is increasing. Little is known about GBS in periprosthetic joint infections (PJIs). We aimed to analyse the clinical presentation of GBS PJI and its treatment in association with the outcome. The characteristics of 36 GBS PJIs collected from 10 centres were investigated. In 34 episodes, follow-up examination of ≥ 2 years was available, allowing treatment and outcome analysis. Most infections (75%) occurred ≥ 3 months after implantation. Most patients (91%) had at least one comorbidity; 69% presented with acute symptoms and 83% with damaged periprosthetic soft tissue. In 20 of 34 episodes debridement and retention of implant was attempted, but in five of these the prosthesis was ultimately removed. Hence, in 19 (56%) episodes, the implant was removed, including 14 immediate removals. In four episodes the removal was permanent. Penicillin derivatives and clindamycin were the most common antimicrobials administered (68%). In 94% the infection was cured, and in 82% functional mobility preserved. Debridement with implant retention was successful if the duration of symptoms was short, the prosthesis stable, and the tissue damage minor (10/10 vs 3/10 episodes, P = 0.003). Surgery that complied with a published algorithm was associated with a favourable outcome (P = 0.049).

Place, publisher, year, edition, pages
Saunders Elsevier, 2011. Vol. 79, no 1, 64-69 p.
Keyword [en]
Group B streptococcus, prosthesis-related infections, streptococcus
National Category
Infectious Medicine
Research subject
Clinical Bacteriology
URN: urn:nbn:se:umu:diva-87766DOI: 10.1016/j.jhin.2011.04.022ISI: 000293781800014PubMedID: 21764170OAI: diva2:711047
Available from: 2014-04-09 Created: 2014-04-09 Last updated: 2014-06-04Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Widerström, Micael
In the same journal
Journal of Hospital Infection
Infectious Medicine

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 28 hits
ReferencesLink to record
Permanent link

Direct link