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Improved estimates of the radiation absorbed dose to the urinary bladder wall
Medical Radiation Physics, Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Malmö, Sweden .
Medical Radiation Physics, Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Malmö, Sweden .
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
Medical Radiation Physics, Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Malmö, Sweden .
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2014 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 59, no 9, 2173-2182 p.Article in journal (Refereed) Published
Abstract [en]

Specific absorbed fractions (SAFs) have been calculated as a function of the content in the urinary bladder in order to allow more realistic calculations of the absorbed dose to the bladder wall. The SAFs were calculated using the urinary bladder anatomy from the ICRP male and female adult reference computational phantoms. The urinary bladder and its content were approximated by a sphere with a wall of constant mass, where the thickness of the wall depended on the amount of urine in the bladder. SAFs were calculated for males and females with 17 different urinary bladder volumes from 10 to 800 mL, using the Monte Carlo computer program MCNP5, at 25 energies of mono-energetic photons and electrons ranging from 10 KeV to 10 MeV. The decay was assumed to be homogeneously distributed in the urinary bladder content and the urinary bladder wall, and the mean absorbed dose to the urinary bladder wall was calculated. The Monte Carlo simulations were validated against measurements made with thermoluminescent dosimeters. The SAFs obtained for a urine volume of 200 mL were compared to the values calculated for the urinary bladder wall using the adult reference computational phantoms. The mean absorbed dose to the urinary wall from F-18-FDG was found to be 77 mu Gy/MBq formales and 86 mu Gy/MBq for females, while for (99)mTc-DTPA the mean absorbed doses were 80 mu Gy/MBq for males and 86 mu Gy/MBq for females. Compared to calculations using a constant value of the SAF from the adult reference computational phantoms, the mean absorbed doses to the bladder wall were 60% higher for F-18-FDG and 30% higher for (99)mTc-DTPA using the new SAFs.

Place, publisher, year, edition, pages
Institute of Physics Publishing (IOPP), 2014. Vol. 59, no 9, 2173-2182 p.
Keyword [en]
dosimetry, urinary bladder, radiation, absorbed dose, dynamic SAF value
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:umu:diva-89204DOI: 10.1088/0031-9155/59/9/2173ISI: 000334598100007OAI: oai:DiVA.org:umu-89204DiVA: diva2:720325
Available from: 2014-05-28 Created: 2014-05-26 Last updated: 2017-12-05Bibliographically approved

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