Change search
ReferencesLink to record
Permanent link

Direct link
Articulatory closure proficiency in Parkinson's disease patients following deep brain stimulation of the subthalamic nucleus and caudal zona incerta.
Umeå University, Faculty of Arts, Department of language studies. Umeå University, Faculty of Medicine, Department of Clinical Sciences, Speech and Language Therapy.ORCID iD: 0000-0003-3373-0934
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Otorhinolaryngology.
Show others and affiliations
2014 (English)In: Journal of Speech, Language and Hearing Research, ISSN 1092-4388, E-ISSN 1558-9102, Vol. 57, 1178-1190 p.Article in journal (Refereed) Published
Abstract [en]


The present study aimed at comparing the effects of deep brain stimulation (DBS) treatment of the subthalamic nucleus (STN) and the caudal zona incerta (cZi) on Parkinson's disease patients' proficiency in achieving oral closure and release during plosive production. METHODS Nineteen patients were evaluated preoperatively and 12 months after DBS surgery. Nine patients were implanted in the STN, seven bilaterally and two unilaterally (left). Ten were bilaterally implanted in the cZi. Postoperative examinations were made off and on stimulation. All patients received simultaneous L-dopa treatment in all conditions. For a series of plosives extracted from a reading passage, absolute and relative measures of duration of frication and amplitude of plosive release were compared between conditions within each treatment group. RESULTS Relative duration of frication increased in voiceless plosives in the on stimulation condition in cZi patients. Similar trends were observed across the data set. Duration of pre-release frication and the release peak prominence increased in voiceless plosives on stimulation for both groups. CONCLUSIONS The increased release prominence suggests that patients achieved a stronger closure gesture due to DBS, but that the increased energy available resulted in increased frication.

Place, publisher, year, edition, pages
2014. Vol. 57, 1178-1190 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:umu:diva-90957DOI: 10.1044/2014_JSLHR-S-13-0010ISI: 000348198000004PubMedID: 24686561OAI: diva2:732476
Available from: 2014-07-04 Created: 2014-07-04 Last updated: 2015-02-18Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Karlsson, FredrikOlofsson, KatarinaBlomstedt, PatricLinder, JanNordh, Erikvan Doorn, Jan
By organisation
Department of language studiesSpeech and Language TherapyOtorhinolaryngology
In the same journal
Journal of Speech, Language and Hearing Research
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 96 hits
ReferencesLink to record
Permanent link

Direct link