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Epidemiology of Influenza Virus Types and Subtypes in South Africa, 2009-2012
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2014 (English)In: Emerging Infectious Diseases, ISSN 1080-6040, E-ISSN 1080-6059, Vol. 20, no 7, 1162-1169 p.Article in journal (Refereed) Published
Abstract [en]

To determine clinical and epidemiologic differences between influenza caused by different virus types and subtypes, we identified patients and tested specimens. Patients were children and adults hospitalized with confirmed influenza and severe acute respiratory illness (SARI) identified through active, prospective, hospital-based surveillance from 2009-2012 in South Africa. Respiratory specimens were tested, typed, and subtyped for influenza virus by PCR. Of 16,005 SARI patients tested, 1,239 (8%) were positive for influenza virus. Patient age and co-infections varied according to virus type and subtype, but disease severity did not. Case-patients with influenza B were more likely than patients with influenza A to be HIV infected. A higher proportion of case-patients infected during the first wave of the 2009 influenza pandemic were 5-24 years of age (19%) than were patients infected during the second wave (9%). Although clinical differences exist, treatment recommendations do not differ according to subtype; prevention through vaccination is recommended.

Place, publisher, year, edition, pages
Atlanta, USA: Centers Disease Control , 2014. Vol. 20, no 7, 1162-1169 p.
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Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:umu:diva-91368DOI: 10.3201/eid2007.131869ISI: 000338389900009OAI: diva2:737824
Available from: 2014-08-14 Created: 2014-08-04 Last updated: 2014-08-14Bibliographically approved

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Kahn, Kathleen
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