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The assiciation of immune cell infiltration and prognosis in colorectal cancer
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.ORCID iD: 0000-0002-9933-2843
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
2013 (English)In: Current colorectal cancer reports, ISSN 1556-3790, Vol. 9, no 4, 372-379 p.Article in journal (Refereed) Published
Abstract [en]

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. The tumor microenvironment is of great biological importance in cancer development and progression and harbors several different immune cells representing both the innate and the adaptive immune response. These inflammatory cells may have both tumor-promoting and tumor-suppressing effects, and they have been shown to be of prognostic importance. This review summarizes the recent evidence regarding the prognostic significance of the host response to colorectal cancer.

Place, publisher, year, edition, pages
Springer, 2013. Vol. 9, no 4, 372-379 p.
Keyword [en]
Colorectal cancer, inflammation, prognosis, immunity, metastatic, microsatellite instability
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:umu:diva-92165DOI: 10.1007/s11888-013-0192-3OAI: oai:DiVA.org:umu-92165DiVA: diva2:739863
Available from: 2014-08-22 Created: 2014-08-22 Last updated: 2015-03-24Bibliographically approved

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Palmqvist, RichardWikberg, Maria LLing, AgnesEdin, Sofia
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