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Effectiveness and cost-effectiveness of individually tailored Internet-delivered cognitive behavior therapy for anxiety disorders in a primary care population: A randomized controlled trial
Department of Behavioural Sciences and Learning, Linköping University, SE-581 83 Linköping, Sweden.
Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, 171 77 Stockholm, Sweden.
Department of Behavioural Sciences and Learning, Linköping University, SE-581 83 Linköping, Sweden.
Department of Behavioural Sciences and Learning, Linköping University, SE-581 83 Linköping, Sweden.
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2014 (English)In: Behaviour Research and Therapy, ISSN 0005-7967, E-ISSN 1873-622X, Vol. 59, 1-11 p.Article in journal (Refereed) Published
Abstract [en]

A significant proportion of the general population suffers from anxiety disorders, often with comorbid psychiatric conditions. Internet-delivered cognitive behavior therapy (ICBT) has been found to be a potent treatment for patients with specific psychiatric conditions. The aim of this trial was to investigate the effectiveness and cost-effectiveness of ICBT when tailoring the treatment to address comorbidities and preferences for primary-care patients with a principal anxiety disorder. One hundred participants were recruited through their primary-care contact and randomized to either treatment or an active control group. The treatment consisted of 7-10 weekly individually assigned modules guided by online therapists. At post-treatment, 46% of the treatment group had achieved clinically significant improvement on the primary outcome measure (CORE-OM) and between-group effect sizes ranged from d = 0.20 to 0.86, with a mean effect of d = 0.59. At one-year follow-up, within-group effect sizes varied between d = 0.53 to 1.00. Cost analysis showed significant reduction of total costs for the ICBT group, the results were maintained at one-year follow-up and the incremental cost-effectiveness ratio favored ICBT compared to control group. Individually tailored ICBT is an effective and cost-effective treatment for primary-care patients with anxiety disorders with or without comorbidities. Trial Registration: NCT01390168. (C) 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (

Place, publisher, year, edition, pages
Elsevier, 2014. Vol. 59, 1-11 p.
Keyword [en]
Primary care, Anxiety, Depression, Comorbidity, Internet-delivered cognitive behavior therapy, Cognitive behavior, Cost-effectiveness
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URN: urn:nbn:se:umu:diva-92633DOI: 10.1016/j.brat.2014.05.007ISI: 000340224000001PubMedID: 24933451OAI: diva2:747902
Available from: 2014-09-17 Created: 2014-09-01 Last updated: 2014-09-19Bibliographically approved

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Eriksson, StinaLindkvist, Emelie
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