Change search
ReferencesLink to record
Permanent link

Direct link
Three dimensional distribution of Propionibacterium acnes biofilms in human skin
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
Umeå University, Faculty of Medicine, Department of Medical Biosciences, Pathology.
2014 (English)In: Experimental dermatology, ISSN 0906-6705, E-ISSN 1600-0625, Vol. 23, no 9, 687-689 p.Article in journal (Refereed) Published
Abstract [en]

Propionibacterium acnes is regarded as a common member of the human skin microbiota, often occurring in biofilms. Little is known about the size of bacterial biofilms in hair follicles as a few sections of biopsy tissue are routinely evaluated. Transversal sectioning provides a better opportunity for histological analyses of hair follicles which can be followed through the different morphological levels. Direct visualization of P.acnes biofilms in hundreds of consecutive sections allowed insight into the 3D distribution in human hair follicles as well as investigating the depth of biofilm distribution within hair follicles. Four distinct colonization patterns of P.acnes biofilms were revealed. Results have shown that an individual P.acnes biofilm can spread for 1900m in a terminal hair follicle. This information can be of help while designing potential antibiofilm treatment.

Place, publisher, year, edition, pages
John Wiley & Sons, 2014. Vol. 23, no 9, 687-689 p.
Keyword [en]
biofilm, hair follicle, P, acnes, skin
National Category
Medical and Health Sciences
Research subject
URN: urn:nbn:se:umu:diva-94925DOI: 10.1111/exd.12482ISI: 000342132800019OAI: diva2:762000
Available from: 2014-11-10 Created: 2014-10-20 Last updated: 2014-11-10Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Jahns, Anika C.Alexeyev, Oleg A.
By organisation
In the same journal
Experimental dermatology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 97 hits
ReferencesLink to record
Permanent link

Direct link