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Partial Volume Correction of Cerebral Perfusion Estimates Obtained by Arterial Spin Labeling
Umeå University, Faculty of Medicine, Department of Radiation Sciences. Umeå University, Faculty of Science and Technology, Centre for Biomedical Engineering and Physics (CMTF).
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics. Umeå University, Faculty of Medicine, Umeå Centre for Functional Brain Imaging (UFBI).
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2015 (English)In: 16th Nordic-Baltic Conference on Biomedical Engineering: 16. NBC & 10. MTD 2014 joint conferences. October 14-16, 2014, Gothenburg, Sweden, 2015, Vol. 48, 17-19 p.Conference paper, Published paper (Refereed)
Abstract [en]

Arterial Spin labeling (ASL) is a fully non-invasive MRI method capable to quantify cerebral perfusion. However, gray (GM) and white matter (WM) ASL perfusions are difficult to assess separately due to limited spatial resolution increasing the partial volume effects (PVE). In the present study, ASL PVE correction was implemented based on a regression algorithm in 22 healthy young men. PVE corrected perfusion of GM and WM were compared to previous studies. PVE-corrected GM perfusion was in agreement with literature values. In general, WM perfusion was higher despite the use of PVE correction.

Place, publisher, year, edition, pages
2015. Vol. 48, 17-19 p.
Series
IFMBE Proceedings, ISSN 1680-0737 ; 48
Keyword [en]
MRI, cerebral perfusion, gray and white matter, arterial spin labeling and healthy
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:umu:diva-100142DOI: 10.1007/978-3-319-12967-9_5ISI: 000347893000005ISBN: 978-3-319-12966-2 (print)ISBN: 978-3-319-12967-9 (print)OAI: oai:DiVA.org:umu-100142DiVA: diva2:791117
Conference
16th Nordic-Baltic Conference on Biomedical Engineering, October 14-16, 2014, Gothenburg, Sweden
Available from: 2015-02-26 Created: 2015-02-24 Last updated: 2015-10-01Bibliographically approved

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Ambarki, KhalidWahlin, AndersZarrinkoob, LalehMalm, JanEklund, Anders
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Department of Radiation SciencesCentre for Biomedical Engineering and Physics (CMTF)Radiation PhysicsUmeå Centre for Functional Brain Imaging (UFBI)
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CiteExportLink to record
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Citation style
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