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Detection of a 640-bp deletion in the Aggregatibacter actinomycetemcomitans leukotoxin promoter region in isolates from an adolescent of Ethiopian origin
Umeå University, Faculty of Medicine, Department of Odontology. (Aa-gruppen)
Östersund, Sweden.
Umeå University, Faculty of Medicine, Department of Odontology. (Aa-gruppen)
Aarhus, Denmark.
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2015 (English)In: Journal of Oral Microbiology, ISSN 2000-2297, E-ISSN 2000-2297, Vol. 7, 26974Article in journal (Refereed) Published
Abstract [en]

The expression of the leukotoxin of Aggregatibacter actinomycetemcomitans is regulated by the leukotoxin promoter. A 530-bp deletion or an 886-bp insertion sequence (IS) element in this region has earlier been described in highly leukotoxic isolates. Here, we report on highly leukotoxic isolate with a 640-bp deletion, which was detected in an adolescent of Ethiopian origin.

Place, publisher, year, edition, pages
CoAction Publishing, 2015. Vol. 7, 26974
Keyword [en]
Aggregatibacter actinomycetemcomitans, leukotoxicity, deletion, JP2, aggressive periodontitis, geographic spreading, Africa
National Category
Microbiology in the medical area Dentistry
Research subject
URN: urn:nbn:se:umu:diva-101986DOI: 10.3402/jom.v7.26974ISI: 000365696700001PubMedID: 25881573OAI: diva2:806186
Available from: 2015-04-18 Created: 2015-04-18 Last updated: 2015-12-28Bibliographically approved

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Claesson, RolfHöglund-Åberg, CarolaJohansson, Anders
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