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Prevalence of diastolic dysfunction in patients with ankylosing spondylitis: a cross-sectional study
Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg.
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2015 (English)In: Scandinavian Journal of Rheumatology, ISSN 0300-9742, E-ISSN 1502-7732, Vol. 44, no 2, 111-117 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: To determine the prevalence of diastolic dysfunction (DD) in patients with ankylosing spondylitis (AS) by following recommended criteria from the American Society of Echocardiography (ASE) and using single variables reflecting DD.

METHOD: A total of 187 patients with AS (105 men; mean age 51 ± 13 years; mean duration of disease 15 ± 11 years) fulfilled the inclusion criteria and underwent pulsed-wave and tissue Doppler imaging.

RESULTS: By following ASE recommended criteria, we observed that 12% of patients with AS had mild DD. We also compared single standard Doppler values with normal age-stratified reference values and showed a wide variation in the number of patients with AS outside the 95% confidence interval (CI) of normal values depending on the variable chosen (ranging from 1.1% to 30.5%).

CONCLUSIONS: By following recommended criteria, our cross-sectional study shows that DD was infrequent and mild in patients with AS.

Place, publisher, year, edition, pages
Taylor & Francis, 2015. Vol. 44, no 2, 111-117 p.
National Category
Rheumatology and Autoimmunity
URN: urn:nbn:se:umu:diva-102958DOI: 10.3109/03009742.2014.953201ISI: 000351182100005PubMedID: 25421143OAI: diva2:811494
Available from: 2015-05-12 Created: 2015-05-12 Last updated: 2016-03-21Bibliographically approved

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Forsblad-d'Elia, Helena
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