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Enhanced peak oxygen consumption and fat oxidation following resistance training with emphasis on muscular hypertrophy
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Sports Medicine.
2012 (English)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Heavy resistance training is generally associated with muscle hypertrophy and increases in muscular strength and anaerobic capacity. However, the adaptive response in aerobic metabolism is less investigated. The purpose of the present study was therefore to evaluate the effects of heavy resistance training on peak oxygen consumption (VO2peak), rate of fat oxidation during exercise and oxidative enzyme activity. Nineteen healthy young men volunteered to participate in the study. During eight weeks, the subjects performed supervised heavy resistance training with emphasis on muscular hypertrophy. Before and after the training intervention, body composition was assessed by dual energy X-ray absorptiometry and a graded incremental exercise test on a cycle ergometer was performed in order to determine VO2peak and fat oxidation kinetics. Further, skeletal muscle biopsies were taken from m. vastus lateralis before and after training to analyze the activity of the oxidative enzymes citrate synthase (CS) and β-hydroxyacyl-CoA dehydrogenase (β-HAD). The results of the study indicate that heavy resistance training induced major effects on cardiorespiratory capacity (p <0.001) and submaximal substrate utilization (p <0.001) despite no significant changes in oxidative enzyme activity (CS and β-HAD). Instead, part of the increases in VO2peak and rate of fat oxidation may be due to skeletal muscle hypertrophy and neuromuscular adaptations manifested by an increased work economy on the cycle ergometer.

Place, publisher, year, edition, pages
2012. , 27 p.
Keyword [en]
resistance training, hypertrophy, fat oxidation, VO2peak, oxidative enzyme activity
National Category
Sport and Fitness Sciences
URN: urn:nbn:se:umu:diva-103583OAI: diva2:813225
Educational program
Master program in Sports Medicine
Available from: 2015-07-03 Created: 2015-05-21 Last updated: 2015-07-03Bibliographically approved

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