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Nanoteknologia biomateriaalien ja lääkkeiden kantaja-aineiden pintojen räätälöinnissä [Nanoscale tailoring of the surface properties of biomaterials and drug carriers]
Department of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Deaprtment of Environmental Science.
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. (Chondrogenic and Osteogenic Differentiation Group)ORCID iD: 0000-0002-6181-9904
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
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2012 (Finnish)In: Duodecim, ISSN 0012-7183, E-ISSN 2242-3281, Vol. 128, no 20, 2085-2092 p., 23167167Article, review/survey (Refereed) Published
Abstract [en]

Functionalities of biomaterials and drug delivery systems are improved by tailoring their surface properties using modern nanotechnology. Orthopedic implants and invasive electrodes are examples of implantable biomaterials. Biological interactions of orthopedic implants can be optimized by the synergetic effect of surface micro- and nanotexturing with a chemical composition of coating. Further, mechanical flexibility and electrochemical characteristics of invasive electrodes are improved by using micro- and nanotechnology. In nano-size drug delivery systems, surface properties of nanocarriers strongly affect their safety and efficacy. Mesoporous silicon nanoparticles are example of nanocarriers those properties can be tailored for drug delivery applications.

Place, publisher, year, edition, pages
2012. Vol. 128, no 20, 2085-2092 p., 23167167
Keyword [en]
Nanomaterials, Tailored coatings, Drug delivery, Electrodes
National Category
Materials Engineering Materials Chemistry Pharmacology and Toxicology
Research subject
Materials Science; nanomaterials; nanoparticles
Identifiers
URN: urn:nbn:se:umu:diva-104361OAI: oai:DiVA.org:umu-104361DiVA: diva2:819304
Available from: 2015-06-10 Created: 2015-06-10 Last updated: 2017-12-04

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