Comparison of ultrasound and optical coherence tomography techniques for evaluation of integrity of spontaneously repaired horse cartilage.
2012 (English)In: Journal of Medical Engineering & Technology, ISSN 0309-1902, E-ISSN 1464-522X, Vol. 36, no 3, 185-192 p., 22439802Article in journal (Refereed) Published
The aim of this study was to compare sensitivity of ultrasound and optical coherence tomography (OCT) techniques for the evaluation of the integrity of spontaneously repaired horse cartilage. Articular surfaces of horse intercarpal joints, featuring both intact tissue and spontaneously healed chondral or osteochondral defects, were imaged ex vivo with arthroscopic ultrasound and laboratory OCT devices. Quantitative ultrasound (integrated reflection coefficient (IRC), apparent integrated backscattering coefficient (AIB) and ultrasound roughness index (URI)) and optical parameters (optical reflection coefficient (ORC), optical roughness index (ORI) and optical backscattering (OBS)) were determined and compared with histological integrity and mechanical properties of the tissue. Spontaneously healed tissue could be quantitatively discerned from the intact tissue with ultrasound and OCT techniques. Furthermore, several significant correlations (p < 0.05) were detected between ultrasound and OCT parameters. Superior resolution of OCT provided a more accurate measurement of cartilage surface roughness, while the ultrasound backscattering from the inner structures of the cartilage matched better with the histological findings. Since the techniques were found to be complementary to each other, dual modality imaging techniques could provide a useful tool for the arthroscopic evaluation of the integrity of articular cartilage.
Place, publisher, year, edition, pages
Informa Healthcare, 2012. Vol. 36, no 3, 185-192 p., 22439802
Articular cartilage, Cartilage repair, High-frequency ultrasound, Optical coherence tomography, Quantitative characterization
Medical Image Processing Medical Laboratory and Measurements Technologies Orthopedics
Research subject Orthopaedics; Physical Biology
IdentifiersURN: urn:nbn:se:umu:diva-104434DOI: 10.3109/03091902.2012.663054PubMedID: 22439802OAI: oai:DiVA.org:umu-104434DiVA: diva2:819652