Change search
ReferencesLink to record
Permanent link

Direct link
Differences in pre-operative treatment for rectal cancer between Norway, Sweden, Denmark, Belgium and the Netherlands
Show others and affiliations
2014 (English)In: European Journal of Surgical Oncology, ISSN 0748-7983, E-ISSN 1532-2157, Vol. 40, no 12, 1789-1796 p.Article in journal (Refereed) Published
Abstract [en]

Several studies have shown remarkable differences in colorectal cancer survival across Europe. Most of these studies lacked information about stage and treatment. In this study we compared short-term survival as well as differences in tumour stage and treatment strategies between five European countries: Norway, Sweden, Denmark, Belgium, and the Netherlands. For this retrospective cohort study all patients aged 18 years or older and operated on adenocarcinoma of the rectum without distant metastases and diagnosed in 2008 and 2009 were selected in national audit registries from Norway, Sweden, Denmark, Belgium, and the Netherlands. Differences in pre-operative treatment between the countries were compared using univariable and multivariable logistic regression. One year relative survival and one year relative excess risk of death (RER) were compared between the five countries. Large variation in the use of preoperative radiotherapy and chemoradiation was found between the countries. Even though, there was little variation in relative survival between the countries, except Sweden, which had a significant better one year RER of death among the elderly patients after adjustment. The differences in survival are expected to be caused by differences in pen-operative care, selection of patients, and especially management of elderly patients. The effects of preoperative treatment are expected to be seen on long term follow-up. 

Place, publisher, year, edition, pages
2014. Vol. 40, no 12, 1789-1796 p.
Keyword [en]
Rectal neoplasms, Quality assurance, Audit, Population-based, Preoperative treatment, Mortality
National Category
Cancer and Oncology
URN: urn:nbn:se:umu:diva-104150DOI: 10.1016/j.ejso.2014.09.011ISI: 000347585600028PubMedID: 25454831OAI: diva2:823103
Available from: 2015-06-17 Created: 2015-06-08 Last updated: 2015-06-17Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Johansson, Robert
By organisation
In the same journal
European Journal of Surgical Oncology
Cancer and Oncology

Search outside of DiVA

GoogleGoogle ScholarTotal: 1 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 48 hits
ReferencesLink to record
Permanent link

Direct link