Longitudinal changes in muscle mass, strength and function in elderly men: a population-based study
Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Aging is associated with changes in body composition as well as functional and structural decline
The aim of this study was to describe longitudinal changes in muscle mass, muscle strength and function and to investigate the prevalence of, and change in, sarcopenia.
This 5-year longitudinal population-based study included 999 Swedish men aged 70-80 years at baseline, 655 subjects partook in follow-up measures. Lean values were assessed using dual X-ray absorptiometry. Appendicular skeletal muscle mass (ASM) was used to calculate skeletal muscle mass index (SMI) as ASM divided by height squared. Muscle strength and physical function was tested by timed-stands test, 6-m and 20-cm narrow walk test and handgrip test. Sarcopenia was defined using an algorithm from The European Working Group on Sarcopenia in Older People (EWGSOP).
Results showed a significant decrease in all studied variables of strength and function as well as significant decreases in lean parameters. Total body fat increased significantly and no significant change was seen in BMI. The relative decline in strength and function was found to be larger than the relative decline in muscle mass. A larger proportional decrease was found in ASM than the decrease in total body lean. The prevalence of sarcopenia increased fourfold from baseline to follow-up.
The relative decline in strength and function is more rapid than the relative decline in muscle mass in older men. Skeletal muscle mass decreases more rapidly than overall lean mass in older men. Sarcopenia increases significantly with age in older populations.
Place, publisher, year, edition, pages
2015. , 25 p.
Sarcopenia, functional capacity, performance, gait speed
IdentifiersURN: urn:nbn:se:umu:diva-105232OAI: oai:DiVA.org:umu-105232DiVA: diva2:824263
Graduate Programme in Physiotherapy
Ribom, Eva, Docent
Lundin-Olsson, Lillemor, Professor