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Operation for primary cystocele with anterior colporrhaphy or non-absorbable mesh: patient-reported outcomes
The National Quality Register of Gynecological Surgery, Umeå University, Stockholm, Sweden.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Obstetrics and Gynaecology. The National Quality Register of Gynecological Surgery, Umeå University, Stockholm, Sweden.
2015 (English)In: International Urogynecology Journal, ISSN 0937-3462, E-ISSN 1433-3023, Vol. 26, no 3, 359-366 p.Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to compare the results of primary anterior vaginal wall prolapse repair, using standard anterior colporrhaphy or non-absorbable mesh in a routine health care setting. The study was based on prospectively collected data from the Swedish National Register for Gynaecological Surgery. All patients were operated on solely for primary, anterior vaginal wall prolapse between January 2006 and October 2013: 6,247 women had an anterior colporrhaphy, and in 356 a non-absorbable mesh was used. Data were collected from doctors and patients up to 1 year after surgery. The 1-year cure rate for the mesh group was superior to that of the colporrhaphy group with an odds ratio (OR) of 1.53 (CI 1.1-2.13), corresponding to a number needed to treat (NNT) of 13.5. Patient satisfaction, OR = 2.45 (CI 1.58-3.80), and patient improvement, OR 2.99 (CI 1.62-5.54), was also higher in the mesh group. However, patient-reported complications, OR = 1.51 (CI 1.15-1.98), and the incidence of persisting pain in the loin, OR = 3.58 (CI 2.32-5.52), were also higher in the mesh group as were surgeon-reported complications, OR = 2.27 (CI 1.77-2.91), bladder injuries, OR = 6.71 (CI 3.14-14.33), and re-operations within 12 months, OR = 6.87 (CI 3.68-12.80). Mesh reinforcement, in primary anterior vaginal wall prolapse patients, enhanced the likelihood of anatomical success at 1 year after surgery. However, mesh implant was associated with a significantly higher incidence of bladder injury, reoperations, both patient- and surgeon-reported complications, more patient-reported pain and a longer hospital stay.

Place, publisher, year, edition, pages
2015. Vol. 26, no 3, 359-366 p.
Keyword [en]
Cystocele, Colporrhaphy, Non-absorbable mesh, National register data, Patient reported outcome
National Category
URN: urn:nbn:se:umu:diva-101380DOI: 10.1007/s00192-014-2511-xISI: 000349956700008PubMedID: 25266356OAI: diva2:840446
Available from: 2015-07-08 Created: 2015-03-30 Last updated: 2016-05-03Bibliographically approved

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Löfgren, MatsNüssler, Emil Karl
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