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Vitamin D and multiple sclerosis from epidemiology to prevention
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
2015 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 132, no Supplement 199, 56-61 p.Article, review/survey (Refereed) Published
Abstract [en]

In the present review, we discuss observational and experimental data suggesting a protective effect from sun exposure and/or vitamin D in multiple sclerosis (MS). These data include geographic variations in MS occurrence, temporal trends, genetics, biobank, and questionnaire data. We look more closely at the differentiation between general effects from UV exposure, and those of vitamin D per se, including plausible mechanisms of action. Finally, primary prevention is touched upon, and we suggest actions to be taken while awaiting the results from ongoing randomized controlled trials with vitamin D in MS.

Place, publisher, year, edition, pages
2015. Vol. 132, no Supplement 199, 56-61 p.
Keyword [en]
multiple sclerosis, vitamin D, epidemiology, prevention
National Category
Neurology
Identifiers
URN: urn:nbn:se:umu:diva-106487DOI: 10.1111/ane.12432ISI: 000355852600010PubMedID: 26046560OAI: oai:DiVA.org:umu-106487DiVA: diva2:842100
Available from: 2015-07-16 Created: 2015-07-14 Last updated: 2017-12-04Bibliographically approved

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