Volume of blood loss during surgery for colon cancer is a risk eterminant for future small bowel obstruction caused by recurrence-a opulation-based epidemiological study
2015 (English)In: Langenbeck's archives of surgery (Print), ISSN 1435-2443, E-ISSN 1435-2451, Vol. 400, no 5, 599-607 p.Article in journal (Refereed) Published
Small bowel obstruction (SBO) is a serious late complication after bdominal surgery. The pathogenesis of intra-abdominal adhesions has een extensively studied and reviewed, but the cascade of mechanisms nvolved is still not understood. The objective was to test the ypothesis that increasing volume of blood loss during surgery for lon ancer increases the risk for future SBO, mainly due to adhesions. ata were retrieved from the Regional Quality Register for all patients ndergoing locally radical surgery for colon cancer 1997-2003 (n = 3 54) and matched with the Swedish National Patient Register data on urgery and admission for SBO. Records were reviewed to determine the tiology of surgery for SBO. Uni- and multivariate Cox analyses were sed. ne hundred ten patients (3.1 %) underwent surgery for SBO > 30 days fter the index operation. Blood loss a parts per thousand yen250 ml s n independent risk factor for surgery for SBO due to recurrence (HR .20; 95 % CI 1.12-4.31). Amount of blood loss did not affect the risk or surgery for SBO due to adhesions. Furthermore, blood loss of a rts er thousand yen250 ml increased the risk for hospital admission for
Place, publisher, year, edition, pages
2015. Vol. 400, no 5, 599-607 p.
Hemorrhage, Perioperative bleeding, Colorectal neoplasm, Intestinal struction, SBO
IdentifiersURN: urn:nbn:se:umu:diva-107077DOI: 10.1007/s00423-015-1317-8ISI: 000357495700009PubMedID: 26100567OAI: oai:DiVA.org:umu-107077DiVA: diva2:853802