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DengueTools: innovative strategies and tools for the prevention and control of dengue
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. (DengueTools)
2015 (English)In: Tropical medicine & international health, ISSN 1360-2276, E-ISSN 1365-3156, Vol. 20, no Suppl. 1, 36-36 p.Article in journal, Meeting abstract (Other academic) Published
Abstract [en]

With estimated 390 million infections annually and 2.5 billion people at risk, dengue is a major emerging disease threat and an escalating public health problem worldwide. Effective vector control remains elusive, and surveillance in dengue endemic countries remains suboptimal at best. We lack understanding of individual or combined roles of viral, entomological, ecological, environmental and climate factors that influence dengue transmission dynamics and their respective outbreak predictive capability and the most cost-effective approach for surveillance and early warning systems. To address those gaps we have set up a comprehensive, early warning, laboratory-based sentinel disease surveillance system in Sri Lanka that has predictive capability for epidemic dengue. Furthermore, children are the most vulnerable group for dengue. We desperately need simple, cost-effective and scalable control strategies to protect children from dengue. Our DengueTools consortium hypothesized that insecticide treated school uniforms may be a target for school-based intervention to reduce the incidence of dengue in school children. We will report on our preliminary results. Lastly, DengueTools examines gaps in understanding the risk of introduction of dengue to non-infected areas, including Europe. We currently have insufficient data on the magnitude and trends of importation and virus evolution over time and by geographic origin. We also only have a poor understanding of vector density, preferred breeding sites, and vectorial capacity of Aedes in temperate climates that are needed for predictive models under changing climate conditions. We will collect clinical and virological data in travellers returning to Europe from dengue endemic countries, explore the effectiveness of vector control programs against Aedes albopictus in Southern France, and develop predictive risk models and maps the the introduction and establishment of dengue in Europe under different future climate scenarios in Europe. DengueTools is a global consortium of 14 partners, funded by the European commission 7th framework. We have 12 work packages around 3 main research areas.

Disclosure: Principal Investigator of DengueTools. No other conflict of interests since January 2011.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2015. Vol. 20, no Suppl. 1, 36-36 p.
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:umu:diva-109939ISI: 000360758800087OAI: oai:DiVA.org:umu-109939DiVA: diva2:861326
Conference
The 9th European Congress on Tropical Medicine and International Health (ECTMIH), Basel, Switzerland, September 6-10, 2015
Available from: 2015-10-16 Created: 2015-10-09 Last updated: 2015-10-16Bibliographically approved

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