umu.sePublications
Change search
ReferencesLink to record
Permanent link

Direct link
Responses of mammalian cells to mechanical forces
Department of Anatomy, University of Kuopio, Kuopio, Finland. (Chondrogenic and Osteogenic Differentiation Group)ORCID iD: 0000-0002-6181-9904
Department of Anatomy, University of Kuopio, Kuopio, Finland.
Department of Anatomy, University of Kuopio, Kuopio, Finland.
Department of Physiology, University of Kuopio, Kuopio, Finland; Department of Surgery, Kuopio University Hospital, Kuopio, Finland.
Show others and affiliations
2001 (English)In: Recent Research Developments in Biophysics and Biochemistry / [ed] Pandalai, S. G., Trivandrum, India: Research Signpost , 2001, Vol. 1, 77-89 p.Chapter in book (Other academic)
Abstract [en]

All cells and tissues of our body are continuously subject to various mechanical stresses. These forces include, e.g., compression, shear stress, hydrostatic pressure and osmotic pressure. The range of forces vary from few pascals to several megapascals in magnitude. In many cases, mechanical forces are required for the tissues to maintain their normal functional structure and composition. However, excessive forces in the end may lead to adverse responses. In this paper, we review the data available from many different tissues in order to compare the signaling mechanisms involved in cellular mechanotransduction, and how the cells respond to forces that are too strenuous for them to withstand. The possible stress reactions caused by excessive forces are also discussed.

Place, publisher, year, edition, pages
Trivandrum, India: Research Signpost , 2001, Vol. 1. 77-89 p.
Keyword [en]
Biophysics, Mechanobiology, Cell
National Category
Cell and Molecular Biology Biochemistry and Molecular Biology Biophysics
Research subject
Biochemistry; cellforskning; biomechanics
Identifiers
URN: urn:nbn:se:umu:diva-111584ISBN: 81-7736-057-4OAI: oai:DiVA.org:umu-111584DiVA: diva2:871917
Available from: 2015-11-17 Created: 2015-11-17 Last updated: 2015-11-17

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Lammi, Mikko
Cell and Molecular BiologyBiochemistry and Molecular BiologyBiophysics

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 20 hits
ReferencesLink to record
Permanent link

Direct link