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Changing grains for the prevention and treatment of Kashin-Beck disease in children: a Meta-analysis
College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
College of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Department of Surgery, The Second Hospital of Weinan City, Weinan, China.
Department of Laboratory Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
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2015 (English)In: Biomedical and environmental sciences, ISSN 0895-3988, E-ISSN 2214-0190, Vol. 28, no 4, 308-311 p.Article in journal (Refereed) Published
Abstract [en]

To evaluate the efficacy of changing grains on the prevention and treatment of Kashin-Beck Disease (KBD) in children, community-based trials were acquired from seven electronic databases (up to July 2014). As a result, the methodological quality of the six trials that have been included into our analysis was low. The pooled ORs favoring the prevention and treatment effects of changing grains were 0.15 (95% CI: 0.03-0.70) and 2.13 (95% CI: 1.44-3.16) respectively by meta-analysis. Subgroup analysis demonstrated the pooled OR favoring treatment effect of exchanging grains rather than drying grains both compared with endemic grains. The results showed that changing grains had obvious effects on the prevention and treatment of KBD in children. However, the evidences were limited by the potential biases and confounders. Large and well-designed trials are still needed.

Place, publisher, year, edition, pages
Chinese Center for Disease Control and Prevention , 2015. Vol. 28, no 4, 308-311 p.
Keyword [en]
Kashin-Beck disease, cartilage, nutrition, grain
National Category
Nutrition and Dietetics
Research subject
Nutrition
Identifiers
URN: urn:nbn:se:umu:diva-111599DOI: 10.3967/bes2015.043ISI: 000354216700009PubMedID: 25966758OAI: oai:DiVA.org:umu-111599DiVA: diva2:872039
Available from: 2015-11-17 Created: 2015-11-17 Last updated: 2016-02-29Bibliographically approved

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Qu, Cheng Juan
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