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The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi. Stress Research Institute, Stockholm University, Stockholm, Sweden.
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2015 (Engelska)Ingår i: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, artikel-id 371905Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Introduction: Atrial fibrillation (AF) is a common heart rhythmdisorder. Several life-style factors have been identified as risk factors for AF, but less is known about the impact of work-related stress. This study aims to evaluate the association between work-related stress, defined as job strain, and risk of AF. Methods: Data from the Swedish WOLF study was used, comprising 10,121 working men and women. Job strain was measured by the demand-control model. Information on incident AF was derived from national registers. Cox proportional hazard regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between job strain and AF risk. Results: In total, 253 incident AF cases were identified during a total follow-up time of 132,387 person-years. Job strain was associated with AF risk in a time-dependent manner, with stronger association after 10.7 years of follow-up (HR 1.93, 95% CI 1.10-3.36 after 10.7 years, versus HR 1.11, 95% CI 0.67-1.83 before 10.7 years). The results pointed towards a dose-response relationship when taking accumulated exposure to job strain over time into account. Conclusion: This study provides support to the hypothesis that work-related stress defined as job strain is linked to an increased risk of AF.

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Hindawi Publishing Corporation, 2015. artikel-id 371905
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Kardiologi Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) Psykologi
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URN: urn:nbn:se:umu:diva-112025DOI: 10.1155/2015/371905ISI: 000364059500001OAI: oai:DiVA.org:umu-112025DiVA, id: diva2:874895
Tillgänglig från: 2015-11-30 Skapad: 2015-11-30 Senast uppdaterad: 2018-06-07Bibliografiskt granskad

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Nordin, Maria

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KardiologiMedicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci)Psykologi

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