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Toxicology of metals: overview, definitions, concepts, and trends
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
2015 (English)In: Handbook on the toxicology of metals: Volume I: General considerations / [ed] Gunnar F. Nordberg, Bruce A. Fowler, Monica Nordberg, Academic Press, 2015, 4, 3-14 p.Chapter in book (Refereed)
Abstract [en]

Metals and their compounds have long been recognized as important toxic agents, causing acute and chronic poisoning cases in occupational settings and in environmental high-exposure situations. In recent years it has been demonstrated in epidemiological studies that exposures in the general environment to low levels of toxic metals may make an important contribution to the global burden of disease. Furthermore, deficient intakes of essential metals through food give rise to a considerable burden of disease from a global perspective. There is an obvious need for preventive action to decrease this global burden of disease. It is also important to address current concerns for possible increases of metal exposures. This chapter highlights such concerns in relation to the current status of the scientific understanding of the metals included and discussed fully in the relevant chapters of this Handbook. Furthermore, it draws attention to future directions for generating new knowledge to fill gaps in the continued quest to assemble the knowledge base necessary for the protection of human health from adverse consequences related to exposure to metals.

Place, publisher, year, edition, pages
Academic Press, 2015, 4. 3-14 p.
Keyword [en]
global burden of disease, historical perspectives, risk assessment, metal poisoning, adverse effects of low-level exposure
National Category
Environmental Health and Occupational Health
URN: urn:nbn:se:umu:diva-112394DOI: 10.1016/B978-0-444-59453-2.00001-9ISBN: 9780123982926OAI: diva2:877372
Available from: 2015-12-07 Created: 2015-12-07 Last updated: 2015-12-07Bibliographically approved

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