umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Fast 4D flow MRI intracranial segmentation and quantification in tortuous arteries
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper. Wisconsin, USA.
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Radiofysik. Umeå universitet, Medicinska fakulteten, Umeå centrum för funktionell hjärnavbildning (UFBI). Department of Radiology, University of Wisconsin – Madison, Madison, Wisconsin, USA.
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper. Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Centrum för medicinsk teknik och fysik (CMTF).
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper.
Visa övriga samt affilieringar
2015 (Engelska)Ingår i: Journal of Magnetic Resonance Imaging, ISSN 1053-1807, E-ISSN 1522-2586, Vol. 42, nr 5, s. 1458-1464Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

PurposeTo describe, validate, and implement a centerline processing scheme (CPS) for semiautomated segmentation and quantification in carotid siphons of healthy subjects. 4D flow MRI enables blood flow measurement in all major cerebral arteries with one scan. Clinical translational hurdles are time demanding postprocessing and user-dependence induced variability during analysis. Materials and MethodsA CPS for 4D flow data was developed to automatically separate cerebral artery trees. Flow parameters were quantified at planes along the centerline oriented perpendicular to the vessel path. At 3T, validation against 2D phase-contrast (PC) magnetic resonance imaging (MRI) and 4D flow manual processing was performed on an intracranial flow phantom for constant flow, while pulsatile flow validation was performed in the internal carotid artery (ICA) of 10 healthy volunteers. The CPS and 4D manual processing times were measured and compared. Flow and area measurements were also demonstrated along the length of the ICA siphon. ResultsPhantom measurements for area and flow were highly correlated between the CPS and 2D measurements (area: R=0.95, flow: R=0.94), while in vivo waveforms were highly correlated (R=0.93). Processing time was reduced by a factor of 4.6 compared with manual processing. Whole ICA measurements revealed a significantly decreased area in the most distal segment of the carotid siphon (P=0.0017), with flow unchanged (P=0.84). ConclusionThis study exhibits fast semiautomated analysis of intracranial 4D flow MRI. Internal consistency was shown through flow conservation along the tortuous ICA siphon, which is typically difficult to assess. J. Magn. Reson. Imaging 2015;42:1458-1464.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2015. Vol. 42, nr 5, s. 1458-1464
Nyckelord [en]
4D flow MRI, vascular, segmentation, automated processing
Nationell ämneskategori
Radiologi och bildbehandling
Identifikatorer
URN: urn:nbn:se:umu:diva-111468DOI: 10.1002/jmri.24900ISI: 000363280300033PubMedID: 25847621OAI: oai:DiVA.org:umu-111468DiVA, id: diva2:878454
Tillgänglig från: 2015-12-09 Skapad: 2015-11-13 Senast uppdaterad: 2018-06-07Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Wåhlin, AndersAmbarki, KhalidSpaak, ErikMalm, JanEklund, Anders

Sök vidare i DiVA

Av författaren/redaktören
Wåhlin, AndersAmbarki, KhalidSpaak, ErikMalm, JanEklund, Anders
Av organisationen
Institutionen för strålningsvetenskaperRadiofysikUmeå centrum för funktionell hjärnavbildning (UFBI)Centrum för medicinsk teknik och fysik (CMTF)Klinisk neurovetenskap
I samma tidskrift
Journal of Magnetic Resonance Imaging
Radiologi och bildbehandling

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 211 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf