umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Environmental Regulation of Yersinia Pathophysiology
Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Department of Microbiology, College of Medicine, Howard University, Washington, DC, USA.
Umeå University, Faculty of Science and Technology, Department of Molecular Biology (Faculty of Science and Technology). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). (Francis)ORCID iD: 0000-0001-6817-9535
2016 (English)In: Frontiers in Cellular and Infection Microbiology, E-ISSN 2235-2988, Vol. 6, 25Article in journal (Refereed) Published
Abstract [en]

Hallmarks of Yersinia pathogenesis include the ability to form biofilms on surfaces, the ability to establish close contact with eukaryotic target cells and the ability to hijack eukaryotic cell signaling and take over control of strategic cellular processes. Many of these virulence traits are already well-described. However, of equal importance is knowledge of both confined and global regulatory networks that collaborate together to dictate spatial and temporal control of virulence gene expression. This review has the purpose to incorporate historical observations with new discoveries to provide molecular insight into how some of these regulatory mechanisms respond rapidly to environmental flux to govern tight control of virulence gene expression by pathogenic Yersinia.

Place, publisher, year, edition, pages
Frontiers Media S.A , 2016. Vol. 6, 25
Keyword [en]
acidity, temperature, metabolism, RovA, c-di-GMP, cAMP, extracytoplasmic stress, transition metals
National Category
Microbiology
Research subject
Microbiology
Identifiers
URN: urn:nbn:se:umu:diva-117568DOI: 10.3389/fcimb.2016.00025ISI: 000371266600001PubMedID: 26973818OAI: oai:DiVA.org:umu-117568DiVA: diva2:908292
Funder
Swedish Research Council, 2014-2105Swedish Research Council, 2014-6652
Note

Research in the author's own laboratories has been possible through the generous past or present funding support of the National Science Foundation of China (#31170133 and #31570132; SC), National Institute of General Medical Sciences of the National Institutes of Health (#SC2 GM105419; KT), Howard University Medical Alumni Association (KT), Medical Research Foundation of Umeå University (MF), Swedish Research Council (#2014-2105; MF), and Swedish Research Council framework grant—antibiotics and infection (#2014-6652; SC, KT, and MF). Work in the laboratory of MF is performed within the framework of the Umeå Centre for Microbial Research—Linnaeus Program.

Available from: 2016-03-02 Created: 2016-03-02 Last updated: 2017-11-30Bibliographically approved

Open Access in DiVA

fulltext(9324 kB)287 downloads
File information
File name FULLTEXT01.pdfFile size 9324 kBChecksum SHA-512
4c4e902bd01f1c13e4f3c4d5794fde9a74c18210353665a06d923ca5d05fa7b09e0c1367988acd6660384e540ae228e53845db548565a0ab7c8d8cd4327e2e6b
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Francis, Matthew S

Search in DiVA

By author/editor
Francis, Matthew S
By organisation
Department of Molecular Biology (Faculty of Science and Technology)Umeå Centre for Microbial Research (UCMR)
In the same journal
Frontiers in Cellular and Infection Microbiology
Microbiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 287 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 285 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf