umu.sePublications
Change search
ReferencesLink to record
Permanent link

Direct link
Sugar Activation for Production of Nucleotide Sugars as Substrates for Glycosyltransferases in Plants
Umeå University, Faculty of Science and Technology, Department of Plant Physiology. Umeå University, Faculty of Science and Technology, Umeå Plant Science Centre (UPSC).ORCID iD: 0000-0001-8685-9665
Umeå University, Faculty of Science and Technology, Department of Plant Physiology. Umeå University, Faculty of Science and Technology, Umeå Plant Science Centre (UPSC).
2015 (English)In: Journal of Applied Glycoscience, ISSN 1880-7291, Vol. 62, no 2, 25-36 p.Article, review/survey (Refereed) Published
Abstract [en]

In order to serve as a glycosyl donor, a sugar or a sugar derivative (e.g. GlcA) needs to be “activated” to a highly energetic state of a nucleotide-sugar. This activation requires the involvement of specific enzymes which produce NDP-sugars (or, in one case, NMP-sugar), using NTP or NDP as substrate. The present review provides concise survey of distinct plant nucleotide-sugar pyrophosphorylases (all using NTP as one of the substrates and differing in sugar specificity) as well as nucleotide-sugar phosphorylases and sucrose synthase (all using NDP as one of substrates). The pyrophosphorylases discussed include UGPase, USPase, UAGPase, AGPase, GMPase (VTC1), and FKGP, whereas phosphorylases include ADP-Glc phosphorylase and GDP-Gal phosphorylase (VTC2/VTC5). We also discuss the activation mechanism of 3-deoxy-D-manno-octulosonic acid (Kdo) by CKS, leading to the formation of a unique NMP-linked sugar (CMP-Kdo).

Place, publisher, year, edition, pages
The Japanese Society of Applied Glycoscience , 2015. Vol. 62, no 2, 25-36 p.
Keyword [en]
Cell wall formation; glycosyltransferases; nucleotide sugars; sugar activation
National Category
Natural Sciences
Research subject
Biochemistry
Identifiers
URN: urn:nbn:se:umu:diva-118718DOI: 10.5458/jag.jag.JAG-2015_003OAI: oai:DiVA.org:umu-118718DiVA: diva2:915687
Funder
Swedish Research Council
Available from: 2016-03-30 Created: 2016-03-30 Last updated: 2016-04-08Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Kleczkowski, Leszek A.Decker, Daniel
By organisation
Department of Plant PhysiologyUmeå Plant Science Centre (UPSC)
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 7 hits
ReferencesLink to record
Permanent link

Direct link