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Current use of diverting stoma in anterior resection for cancer: population-based cohort study of total and partial mesorectal excision
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Kirurgi.
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2016 (Engelska)Ingår i: International Journal of Colorectal Disease, ISSN 0179-1958, E-ISSN 1432-1262, Vol. 31, nr 3, s. 579-585Artikel i tidskrift (Refereegranskat) Published
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Abstract [en]

Purpose A diverting stoma is commonly used to reduce the risk of anastomotic leakage when performing total mesorectal excision (TME) in anterior resection for rectal cancer. The purpose of this study was to evaluate the impact of fecal diversion in relation to partial mesorectal excision (PME).

Methods A retrospective analysis was undertaken on a national cohort, originally created to study the impact of central arterial ligation on patients with increased cardiovascular risk. Some 741 patients operated with anterior resection for rectal cancer during the years 2007 through 2010 were followed up for 53 months. Multivariate logistic regression was used to evaluate the impact of diverting stoma on the risk of anastomotic leakage and permanent stoma, expressed as odds ratios (ORs) and 95 % confidence intervals (CIs).

Results The risk of anastomotic leakage was increased in TME surgery when not using a diverting stoma (OR 5.1; 95 % CI 2.2-11.6), while the corresponding risk increase in PME patients was modest (OR 1.8; 95 % CI 0.8-4.0). At study completion or death, 26 and 13 % of TME and PME patients, respectively, had a permanent stoma. A diverting stoma was a statistically significant risk factor for a permanent stoma in PME patients (OR 4.7; 95 % CI 2.5-9.0), while less important in TME patients (OR 1.8; 95 % CI 0.6-5.5).

Conclusion The benefit of a diverting stoma concerning anastomotic leakage in this patient group seems doubtful. Moreover, the diverting stoma itself may contribute to the high rate of permanent stomas.

Ort, förlag, år, upplaga, sidor
2016. Vol. 31, nr 3, s. 579-585
Nyckelord [en]
Rectal cancer, Defunctioning stoma, Fecal diversion, Permanent stoma
Nationell ämneskategori
Kirurgi Gastroenterologi
Identifikatorer
URN: urn:nbn:se:umu:diva-118987DOI: 10.1007/s00384-015-2465-6ISI: 000371400900012PubMedID: 26670673OAI: oai:DiVA.org:umu-118987DiVA, id: diva2:925879
Tillgänglig från: 2016-05-03 Skapad: 2016-04-07 Senast uppdaterad: 2018-06-07Bibliografiskt granskad

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Rutegård, MartinBoström, PetrusHaapamäki, MarkkuRutegård, Jörgen

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