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Hydration, Ionic Valence and Cross-linking Propensities of Cations Determine the Stability of Lipopolysaccharide Membranes
2014 (English)In: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, ISSN 1364-548X, Vol. 50, no 2, 231-233 p.Article in journal (Refereed) Published
Abstract [en]

The supra-molecular structure of LPS aggregates governs outer membrane permeability and activation of the host immune response during Gram-negative bacterial infections. Molecular dynamics simulations unveil at atomic resolution the subtle balance between cation hydration and cross-linking ability in modulating phase transitions of LPS membranes.

Place, publisher, year, edition, pages
Cambridge: Royal Society of Chemistry, 2014. Vol. 50, no 2, 231-233 p.
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Chemical Sciences
Identifiers
URN: urn:nbn:se:umu:diva-121300DOI: 10.1039/c3cc46918bOAI: oai:DiVA.org:umu-121300DiVA: diva2:931906
Funder
Swedish National Infrastructure for Computing (SNIC)
Available from: 2016-05-31 Created: 2016-05-31 Last updated: 2016-06-29

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Soares, Tereza A.
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ReferencesLink to record
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