umu.sePublications
Change search
ReferencesLink to record
Permanent link

Direct link
Trace element research-historical and future aspects.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
2016 (English)In: Journal of Trace Elements in Medicine and Biology, ISSN 0946-672X, E-ISSN 1878-3252Article in journal (Refereed) Epub ahead of print
Abstract [en]

During the last 30 years the International Society for Trace Element Research and the Nordic Trace Element Society has been active . During this period the importance of these elements for human diseases has been increasingly recognized, including their contribution to the global burden of disease. New analytical methods allow biomonitoring data to be related to health outcome. Future research using modern chemical methods will focus more on elemental speciation and on measuring lower concentrations leading to further identifying adverse effects and critical organs. Extensive knowledge about essentiality and toxicity of trace elements in humans has emerged during the last two decades and at present the difficulties in defining a range of acceptable oral intakes for essential elements has largely been overcome. Biological monitoring of trace element concentrations in various media such as blood or urine is of great importance and an overview is given. As an example, a more detailed description of biological monitoring of cadmium is given, explaining biokinetics including the role of metallothionein in modifying kinetics and toxicity. Finally future challenges related to risk assessment of newly developed metallic nanomaterials and metal containing medical devices are discussed.

Place, publisher, year, edition, pages
2016.
National Category
Environmental Health and Occupational Health
Identifiers
URN: urn:nbn:se:umu:diva-121532DOI: 10.1016/j.jtemb.2016.04.006PubMedID: 27238729OAI: oai:DiVA.org:umu-121532DiVA: diva2:933089
Available from: 2016-06-03 Created: 2016-06-03 Last updated: 2016-06-03

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Nordberg, Gunnar F
By organisation
Occupational and Environmental Medicine
In the same journal
Journal of Trace Elements in Medicine and Biology
Environmental Health and Occupational Health

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 39 hits
ReferencesLink to record
Permanent link

Direct link